tazemetostat will minimize the extent or effect of pazopanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Otesezonale, a BCRP inhibitor, might boost the effects and chance of toxicities of BCRP substrates. Use cheapest starting off dose of BCRP substrate, or consider lowering BCRP substrate dose.
This medication might be prescribed for other takes advantage of; check with your physician or pharmacist To find out more.
nilutamide will increase the amount or result of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Avoid coadministration of pazopanib with solid CYP3A4 inhibitors if at all possible; if ought to coadminister, lessen pazopanib dose to four hundred mg/day
Really serious - Use Different (one)aluminum hydroxide/magnesium carbonate will lower the extent or impact of pazopanib by raising gastric pH. Applies only to oral kind of both agents.
Pazopanib is a sort of specific cancer drug named a tyrosine kinase inhibitor (TKI). Tyrosine kinase inhibitors do the job by blocking sure proteins (called tyrosine kinases) from performing on cells. Tyrosine kinases sign to cancer cells to expand.
Stay clear of or Use Alternate Drug. Keep away from coadministration of pazopanib with prescription drugs that raise gastric pH; might use limited-acting antacids instead of PPIs and H2 antagonists, but different antacid and pazopanib dosing by a number of hours
acetazolamide will improve the stage or influence of pazopanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.
You must bring this list with you every Pregnanediol time you go to a physician or For anyone who is admitted to a hospital. Additionally it is significant information and facts to carry with you in case of emergencies.
Monitor Intently (1)pazopanib will improve the level or influence of Verapamil hydrochloride lemborexant by Salvianolic Acid C affecting hepatic/intestinal enzyme CYP3A4 metabolism.
deferasirox will minimize the level or result of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
eslicarbazepine acetate will minimize the level or influence of pazopanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
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omeprazole will lessen the level or result of pazopanib by rising gastric pH. Applies only to oral sort of both equally agents.